一﹑基本信息

袁文雅, 博士, 教授, 博士生导师

电子邮件: wyyuan@hubu.edu.cn, yuanwenya@126.com

通讯地址: 湖北省武汉市武昌区友谊大道368号威廉williamhill官网

社会兼职: 湖北省第十，十一届植物生理与分子生物学学会理事; 湖北省第十，十一届遗传学会理事; 民盟武汉市第十四届委员会科技工作委员会副主任

研究领域: 植物功能基因组学、表观遗传学

二﹑教育背景

2002.09–2009.06 华中农业大学生命科学技术学院, 博士

1998.09–2002.06 华中农业大学生命科学技术学院, 学士

三﹑工作经历

2017.05   至今    威廉williamhill官网, 教授

2016.04–2017.02 诺莱生物医学研究院（北京）有限公司上海研发部, 高级研发科学家

2014.07–2016.03 中科院植物逆境生物学研究中心, 副研究员

2009.07–2014.06 新加坡国立大学/淡马锡生命科学实验室, 博士后

四﹑科研项目

1. 湖北省自然科学基金杰出青年人才项目(2019CFA096): 拟南芥春化中CME-VALs-H3K27me3互作介导FLC沉默的遗传机制研究, 2019.09–2022.08, 主持。

2. 湖北省中央引导地方科技发展专项(2019ZYYD028): 湖北省植物倍性种质创新与绿色应用工程研究中心创新平台建设，2019.07–2020.06，主持。

3. 国家自然科学基金面上项目(31872811): VALs蛋白调控拟南芥开花的遗传机制, 2019.01–2022.12，主持。

五﹑发表论文（^#并列一作, ^*通讯作者）

（一）第一作者或通讯作者文章

1. Su Xue^#, Zhang Xiaolong^#, Luo Jie, Wang Yu, Feng Bin, Yang Yanqi, Zhang Biaoming, Li Yan, Zhang Haitao^*, Yuan Wenya^*, Li Haitao^* (2025). The IAA7-ARF7-ARF19 auxin signaling module plays diverse roles in Arabidopsis growth and development. Planta, 262, 12.

2. Li Yan, Guo Xuelian, Song Jiayi, Xu Kun, Qin Tian, Zhang Xianhua, Song Zhaojian, He Yuchi, Zhang Biaoming, Zhang Haitao, Li Haitao, Yuan Wenya^* (2025). OsSPL14 and OsNF-YB9/YC8-12 subunits cooperate to enhance grain appearance quality through promoting Waxy and PDIL1-1 in rice. Plant Communications, 6, 101348.

3. Wang Dekun^#, Yang Ruojiao^#, Liu Mengting^#, Li Haolong, Li Haitao^*, Yuan Wenya^*, Zhang Haitao^* (2025). Recent advances in innovative strategies for plant disease resistance breeding. Frontiers in Plant Science, 16, 1586375.

4. Guo Xuelian^#, Song Jiayi^#, Xu Kun^#, Xu Chunxue, Li Haitao, Zhang Biaoming, Zhang Haitao, Yuan Wenya^*, Li Yan^* (2025). PDIL2-3 encoding a protein disulphide isomerase-like enzyme is involved in determining grain size and quality in rice (Oryza sativa L.). The Crop Journal. (https://doi.org/10.1016/j.cj.2025.02.011)

5. Zhang Xiaolong^#, Feng Bin^#, Wang Yu, Mu Tingting, Zheng Ming, Gao Changbin, Yuan Wenya^*, Hua Wei^*，Li Haitao^* (2025). Targeted disruption of five Bna.BRC1 homologs in rapeseed generates a highly branched germplasm for its multifunctional utilization. Plant Communications, 6, 101319.

6. Feng Bin^#, Wang Yu^#, Zhang Xiaolong, Mu Tingting, Zhang Biaoming, Li Yan, Zhang Haitao, Hua Wei, Yuan Wenya^*, Li Haitao^* (2025). Targeted mutagenesis and functional marker development of two Bna.TAC1s conferring novel rapeseed germplasm with compact architecture. Theoretical and Applied Genetics, 138, 86.

7. Zhu Chengcheng^#, Chen Chuanyou^#, Gong Xia, Li Haitao, Li Yan, Zhang Biaoming^*, Zhang Haitao^*, Yuan Wenya^* (2025). TOUSLED KINASE INTERACTING PROTEIN 1 (TKI1) interacts with SIN3-LIKEs (SNLs) to promote flowering in Arabidopsis. Plant Physiology and Biochemistry, 222, 109761.

8. Huang Can, Wang Diao, Yang Yanqi, Yang Hong, Zhang Biaoming, Li Haitao, Zhang Haitao, Li Yan^*, Yuan Wenya^* (2024). SUPPRESSOR OF FRIGIDA 4 cooperates with the histone methylation reader EBS to positively regulate root development. Plant Physiology, 196, 2199–2212.

9. Zhang Xiaolong^#, Chen Yingying^#, Chen Hongyu, Guo Chaocheng, Su Xue, Mu Tingting, Feng Bin, Wang Yu, Liu Zhixin, Zhang Biaoming, Li Yan, Zhang Haitao, Yuan Wenya^*, Li Haitao^* (2024). Genome-wide analysis of TOPLESS/TOPLESS-RELATED co-repressors and functional characterization of BnaA9.TPL regulating the embryogenesis and leaf morphology in rapeseed. Plant Science, 346, 112149.

10. Yang Yanqi^#, Tian Hao^#, Xu Chunxue, Li Haitao, Li Yan, Zhang Haitao, Zhang Biaoming^*, Yuan Wenya^* (2023). Arabidopsis SEC13B interacts with Suppressor of Frigida 4 to repress flowering. International Journal of Molecular Sciences, 24, 17248.

11. Li Yan^#*, He Yizhou^#, Qin Tian^#, Guo Xuelian, Xu Kun, Xu Chunxue, Yuan Wenya^* (2023). Functional conservation and divergence of miR156 and miR529 during rice development. The Crop Journal, 11, 692–703.

12. Zhang Biaoming^#, Liu Mengting^#, Wang Yanchao^#, Yuan Wenya^*, Zhang Haitao^* (2022). Plant NLRs: evolving with pathogen effectors and engineerable to improve resistance. Frontiers in Microbiology, 13, 1018504.

13. Li Yan^#, He Yizhou^#, Liu Zhixin, Qin Tian, Wang Lei, Chen Zhihui, Zhang Biaoming, Zhang Haitao, Li Haitao, Liu Li, Zhang Jian, Yuan Wenya^* (2022). OsSPL14 acts upstream of OsPIN1b and PILS6b to modulate axillary bud outgrowth by fine-tuning auxin transport in rice. The Plant Journal, 111, 1167–1182.

14. Chen Chuanyou^#, Gong Xia^#, Li Yan, Li Haitao, Zhang Haitao, Liu Li, Liang Dacheng, Yuan Wenya^* (2022). Interaction analysis between the Arabidopsis transcription repressor VAL1 and transcription coregulators SIN3-LIKEs (SNLs). International Journal of Molecular Sciences, 23, 6987. 

15. Zhang Biaoming, Han Xiaoyuan, Yuan Wenya^*, Zhang Haitao^* (2022). TALEs as double-edged swords in plant–pathogen interactions: Progress, challenges and perspectives. Plant Communications, 3, 100318.

16. Zhou Ying^#*, Lei Fang^#, Wang Qiong, He Weicong, Yuan Bin, Yuan Wenya^* (2020). Identification of novel alleles of the rice blast-resistance gene Pi9 through sequence-based allele mining. Rice, 13, 80.

17. Wang Xiuping^#, Liu Caixiang^#, Li Hongqiang, Zhang Haitao, Ma Ruijing, Zhang Qinwen, Yang Fang, Yuan Wenya^*, Chen Fangfang^* (2019). Metabonomics-assisted label-free quantitative proteomics and transcriptome analysis reveals novel insights into antifungal mechanism of graphene oxide for controlling Fusarium graminearum. Environmental Science: Nano, 6, 3401–3421.

18. Huang Fei^#, Yuan Wenya^#, Tian Shu, Zheng Qijie, He Yuehui^* (2019). Gene mediated long-day induction of flowering but inhibit the floral transtion in short days through histone deacetylation in Arabidopsis. The Plant Journal, 100, 101–113.

19. Yuan Wenya, Luo Xiao, Li Zicong, Yang Wannian, Wang Yizhong, Liu Rui, Du Jiamu, He Yuehui^* (2016). A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis. Nature Genetics, 48, 1527–1534.

20. Yuan Wenya, Li Xingwang, Chang Yuxiao, Wen Ruoyu, Chen Guoxing, Zhang Qifa, Wu Changyin^* (2009). Mutation of a rice gene PAIR3 encoding a coiled-coil protein results in defective chromosome pairing in meiosis. The Plant Journal, 59, 303–315.

（二）其他参与文章

1. Liu Xixi^#, Xia Dandan^#, Luo Jinjin^#, Li Mengyuan^#, Chen Lijuan, Chen Yiting, Huang Jie, Li Yanan, Xu Huayu, Yuan Yang, Cheng Yu, Li Zhiyong, Li Guanghao, Wang Shiyi, Liu Xinyong, Liu Wanning, Zhang Fengyong, Liu Zhichao, Tong Xiaohong, Hou Yuxuan, Wang Yifeng, Ying Jiezheng, Baxodir Ugli Abdullaev Mirtemir, Ergashev Mukhammadjon Arabboevich, Zhang Sanqiang, Yuan Wenya, Xue Dawei, Zhang Jianwei^*, Zhang Jian^* (2025). Global protein interactome mapping in rice using barcode-indexed PCR coupled with HiFi long-read sequencing. Advanced Science, 12, 2416243.

2. Chen Zexi^#, Li Ping^#, He Jianfang^#, Wang Wenbo, Pu Xiaojun, Chen Silin, Gao Bei, Wang Xuewen, Zhu Ruiliang, Yuan Wenya, Liu Li^* (2024). Identification of a novel gene, Bryophyte Co-retained Gene 1, that has a positive role in desiccation tolerance in the moss Physcomitriun patens. Journal of Experimental Botany, 75, 6609–6624. 

3. Tang Liqun^#, Wang Huimei^#, Li Guanghao^#, Zhao Juan, Li Zhiyong, Liu Xixi, Shu Yazhou, Liu Wanning, Wang Shuang, Huang Jie, Ying Jiezheng, Tong Xiaohong, Yuan Wenya, Wei Xiangjin, Tang Shaoqing, Wang Yifeng^*, Bu Qingyun^*, Zhang Jian^* (2024). Exogenous abscisic acid repress rice flowering via SAPK8-ABF1-Ehd1/Ehd2 pathway. Journal of Advanced Research, 59, 35–47.

4. Wang Huimei^#, Tong Xiaotong^#, Tang Liqun^#, Wang Yifeng, Zhao Juan, Li Zhiyong, Liu Xixi, Shu Yazhou, Yin Man, Adegoke Tosin Victor, Liu Wanning, Wang Shuang, Xu Huayu, Ying Jiezheng, Yuan Wenya, Yao Jialing, Zhang Jian^* (2022). RLB (RICE LATERAL BRANCH) recruits PRC2-mediated H3K27 tri-methylation on OsCKX4 to regulate lateral branching. Plant Physiology, 188, 460–476.

5. Deng Zhuying, Wu Huiyan, Li Dongyi, Li Luping, Wang Zhipeng, Yuan Wenya, Xing Yongzhong, Li Chendao, Liang Dacheng^* (2021). Root-to-shoot long-distanse mobile miRNAs identified from Nicotiana rootstocks. International Journal of Molecular Sciences, 22, 12821.

6. Pu Xiaojun^#, Yang Lixin^#, Liu Lina, Dong Xiumei, Chen Silin, Chen Zexi, Liu Gaojing, Jia Yanxia, Yuan Wenya, Liu Li^* (2020). Genome-wide analysis of the MYB transcription factor superfamily in Physcomitrella patens. International Journal of Molecular Sciences, 21, 975.

7. Bello Babatunde Kazeem^#, Hou Yuxian^#, Zhao Juan, Jiao Guiai, Wu Yawen, Li Zhiyong, Wang Yifeng, Tong Xiaohong, Wang Wei, Yuan Wenya, Wei Xiangjin, Zhang Jian^* (2019). NF-YB1-YC12-bHLH144 complex directly activates Wx to regulate grain quality in rice (Oryza sativa L.). Plant Biotechnology Journal, 17, 1222–1235.

8. Wang Yizhong, Gu Xiaofeng, Yuan Wenya, Schmitz Robert J., He Yuehui^* (2014). Photoperiodic control of the floral transition through a distinct polycomb repressive complex. Developmental Cell, 28, 727–736.

9. Zhang Cuicui, Yuan Wenya, Zhang Qifa^* (2012). RPL1, a gene involved in epigenetic processes regulates phenotypic plasticity in rice. Molecular Plant, 5, 482–493.

10. Chang Yuxiao, Gong Liang, Yuan Wenya, Li Xingwang, Chen Guoxing, Li Xianghua, Zhang Qifa, Wu Changyin^* (2009). Replication Protein A (RPA1a) is required for meiotic and somatic DNA repair but is dispensable for DNA replication and homologous recombination in rice. Plant Physiology, 151, 2162–2173.

11. Wu Changyin, Li Xiangjun, Yuan Wenya, Chen Guoxing, Kilian Andrzej, Li Juan, Xu Caiguo, Li Xianghua, Zhou Daoxiu, Wang Shiping, Zhang Qifa^* (2003). Development of enhancer trap lines for functional analysis of the rice genome. The Plant Journal, 35, 418–427.

六﹑专利

1. 刘莉、普晓俊、杨卓、杨红、袁文雅。一种通过控制HDS22基因来调控MEcPP含量从而改善植物耐热性的方法。专利号：ZL202110428532.5。

2. 刘莉、杨红、李萍、袁文雅。一种叶绿体蛋白和ATPase酶活性突变体在提高植物抗逆性中的应用。专利号：ZL201910151790.6。

3. 吴昌银、袁文雅、张启发。一种控制水稻花粉育性基因及应用。专利号：ZL20061 0018575.1。

七﹑荣誉

1. 2024年，指导学生获第三届合成生物学创新赛常规赛金奖（第二导师）

2. 2022年，2020级硕士陈传友获国家奖学金

3. 2021年（下半年），威廉williamhill官网本科教学质量优秀

4. 2019年（上半年），威廉williamhill官网本科教学质量优秀

5. 2018年，荣获威廉希尔中国官网教职工年度考核优秀

6. 2018年，入选湖北省“百人计划”科技创新人才

7. 2017年，入选湖北省“楚天学者”特聘教授